The Italian Region of Calabria’s medium- and long-term goals are to promote an inclusive and welcoming community based on lifelong learning and cultural diversity. The Region recognizes the fundamental need of investing in education and knowledge and embraces the 2030 Agenda. In this context, Region Calabria’s local institutions support initiatives focused not only on the promotion of cultural heritage, equity and sustainability, but also the improvement of citizens’ welfare. Yes I start up Calabria is one of the example: project intended for the training and accompaniment to self-employment and self-entrepreneurship, of young NEETs throughout the country, Regional intervention plans for the integration of citizens from third countries /Support to NEET-youth self-employment and self-entrepreneurship and Start-ups support.